Significant differences were found between individuals with NGT, pre-diabetes and T2D, where individuals with T2D were older (p < 0.001), had higher WC (p < 0.001), fasting plasma insulin (p < 0.001), systolic and diastolic blood pressure (p < 0.001) and serum triglycerides (p < 0.001). This evidence concerns the gene INS and type 2 diabetes mellitus.