The SQSTM1 p.Leu268Val has been previously reported in one Italian patient with Alzheimer’s disease (AD) [34]; additionally, we identified another SQSTM1 variant (p.Pro118Ser), which had been previously reported in one patient with ALS, a frontotemporal dementia (FTD) patient, and in two control individuals [34,35]. The gene discussed is SQSTM1; the disease is Alzheimer disease.