CD93 is also present as a soluble form (sCD93), which is an enzymatically cleaved ectodomain of CD93 [4,5], and the sCD93 level or CD93 polymorphisms have been shown to be associated with various inflammatory diseases, such as cerebral ischemia [6], coronary artery disease [7], systemic sclerosis [8], asthma [9], and nasopharyngeal cancer [10]. The gene discussed is CD93; the disease is systemic sclerosis.