Another cross-sectional study of middle-aged Korean adults compared the first adiponectin quartile with those of the fourth quartile and found a decreased risk of MetS (OR: 0.32, 95% CI: 0.20–0.50 for men; OR: 0.57, 95% CI: 0.43–0.76 for women) [19]. The gene discussed is ADIPOQ; the disease is metabolic syndrome.