In our previous study, RT-R-MDA-MB-231 cells released higher levels of IL-1β, which is secreted by inflammasome activation, than MDA-MB-231 cells, and IL-1β was related to tumor progression in MDA-MB-231 and RT-R-MDA-MB-231 cells, suggesting its involvement in tumor aggressiveness. This evidence concerns the gene IL1B and neoplasm.