APOA1 and hepatocellular carcinoma: Nanodiscs generated with apoAI, curcumin, and DMPC was reported to be larger in diameter (~50 nm) compared to that with apoAI and DMPC (5–15 nm) and appeared to inhibit cell growth in hepatoma cells and induce greater apoptotic response (~70%) in mantle cell lymphoma more efficiently than free curcumin (~20%) [161,169].