KIR3DL2 and melanoma: These cells have the characteristic of expressing CD57dimCD69+C-C chemokine receptor type (CCR)7+Killer-cell immunoglobulin-like receptor (KIR)+ on the surface of the cell and have been shown to exhibit strong cytotoxicity against autologous melanoma cells, suggesting that the cytolytic activity of NK cells may not be inhibited in patients with melanoma as has been reported [22].