However, in spite of the crucial role of the liver as a central regulator of iron metabolism, to date, no studies have directly tested the modulation of hepatic gene and protein expression profiles during anemia recovery, including divalent metal transporter 1 (DMT1), ferritin light chain 1 (FTL1), ferroportin 1 (FPN1), and hepcidin antimicrobial peptide (HAMP). The gene discussed is SLC11A2; the disease is anemia.