DEPDC1 and non-small cell lung carcinoma: Subsequently, we carried out the luciferase reporter assays, and the data certified that miR-23b mimics could remarkably repress the activities of DEPDC1 wt1 and wt2 reporters, while the activities of DEPDC1 wt3, DEPDC1 mut1, mut2 and mut3 were not changed, which indicated that miR-23b was directly interacted with DEPDC1 mRNA in NSCLC cells (Figure 7J).