Figure 2(B) shows that medium conditioned by MSC induces the expression of stemness markers, e.g. SOX-2, c-Myc, OCT 3/4, NANOG, and SLC-0111 is able to prevent this enhancement. Moreover, Figure 2(C), shows that SLC-0111 is efficient in inhibiting the in vitro sphere formation induced by cm MSC, an additional assay to reveal stemness in cancer cells. This evidence concerns the gene SOX2 and cancer.