Some of the key recommendations of this working group were: (1) the current payment system should rely less on rebates, discounts, and fees based on list price; (2) health plans should ensure that people with diabetes can access their insulin without undue administrative burden or excessive cost; and (3) pharmacy benefit managers and payers should use rebates to lower the costs for insulin at the point of sale for people with diabetes. The gene discussed is INS; the disease is diabetes mellitus.