As shown in Figure 6D, compared with PD mice injected with saline, the ratios of LC3B-I/LC3B-II and LAMP1/LAMP2 were increased, while the P62 protein expression was decreased in PD mice injected with MPTP or MPTP + LV-oe-NC + agomir-NC (p < 0.05). The gene discussed is LAMP1; the disease is Parkinson disease.