NPTX2 and Parkinson disease: Meanwhile, the ratio of LC3B-I/LC3B-II and LAMP1/LAMP2 was decreased, while the expression of P62 was increased in PD cells treated with oe-HOTAIR + sh-NPTX2 in contrast to oe-HOTAIR + sh-NC treatment (all p < 0.05) (Figure 5B).