As expected, our results verified that exosomal miR‐210‐3p derived from lung CSCs contributed to the pro‐metastatic phenotype of lung cancer cells, including enhanced migratory and invasive abilities as well as up‐regulated expression levels of N‐cadherin, vimentin, MMP‐9 and MMP‐1, with down‐regulated E‐cadherin expression. Here, VIM is linked to lung cancer.