CCNE1 and neoplasm: FBXW7, as a WD40 repeat‐containing protein, targets numerous oncoproteins, including mammalian target of rapamycin, c‐myc, cyclin E, c‐Jun and steroid receptor coactivator‐3 for ubiquitination‐mediated degradation and inhibition of tumour growth.46, 47, 48, 49, 50