Further, WDR41 demethylation or up‐regulation suppressed the proliferative, migratory and tumour formation abilities of MDA‐MB‐231 cells by negatively regulating the AKT/GSK‐3β/β‐catenin signalling pathway, and this effect was attenuated by knockdown of WDR41 (Figure 7). Here, AKT1 is linked to neoplasm.