FBXW7, as a WD40 repeat‐containing protein, targets numerous oncoproteins, including mammalian target of rapamycin, c‐myc, cyclin E, c‐Jun and steroid receptor coactivator‐3 for ubiquitination‐mediated degradation and inhibition of tumour growth.46, 47, 48, 49, 50. This evidence concerns the gene FBXW7 and neoplasm.