In recent years, some scholars have suggested and reported that adipokines secreted by adipose tissue may play an important role in the pathogenesis of obesity and colon cancer using several in vivo, in vitro, and epidemiological investigations [11]; the attention was mainly focused on plasma adiponectin, visfatin, leptin, and resistin [12, 13]. The gene discussed is LEP; the disease is malignant colon neoplasm.