In addition, in order to determine the risk factors for prediabetes-related high-risk colonic polyps, We performed a multivariate unconditional logistic regression analysis adjusted for sex, age, BMI, WHR, 2hPG, FINS, HOMA-IR, adiponectin, current smoking, and family history of colon cancer. The gene discussed is ADIPOQ; the disease is malignant colon neoplasm.