Compared with the polyp-free group with normal glucose tolerance, the average age, plasma visfatin levels, and proportion of family history with colon cancer in the colonic polyps group with normal glucose tolerance were significantly higher (P = 0.032 for age; P = 0.028 for visfatin; P = 0.042 for family history with colon cancer, respectively); plasma adiponectin levels were significantly lower [(9.8 ± 4.8 vs 13.3 ± 3.9) mg/L, P = 0.013], and the other clinical parameters were not statistically significant between the two groups (P > 0.05) (Table 1, Fig. 2). This evidence concerns the gene ADIPOQ and colonic neoplasm.