FLT3 and acute myeloid leukemia: FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD)-mutated acute myeloid leukemia (AML) accounts for up to 30% of adult AML cases, and the prognosis of patients with FLT3-ITD-mutated AML is extremely dismal owing to the high relapse rate after chemotherapy and allogeneic stem cell transplantation [1].