TP53 and ovarian carcinoma: Results of IHC staining analysis showed that P53 and pCDC25CSer216 expressions in the primary ovarian and breast cancer tumors were highly associated in multiple cases, as shown in Fig. 5C and D. According to statistical results (Table 1), P53 and CDC25CSer-216 were positively and negatively expressed in 25 and 13 cases of 51 ovarian carcinomas, respectively.