CCND1 and melanoma: Among the 56 melanoma cases positive by FISH detection, only one case fulfilled all four criteria of Gerami, and nearly half of them fulfilled three criteria, specifically, 18 cases met the criteria “gain of CCND1”, “gain of RREB1”,and “loss of MYB relative to CEP6”, and 8 cases met “gain of RREB1”, “gain of CCND1”, and “gain of RREB1 relative to CEP6”.