BAP1 and cancer: Besides the above described M-associated genes, CDKN2A, NF2 and BAP1, other interesting (and not previously described) genes carried a copy number loss (EP300, SETD2 and PBRM1) and four cancer-associated genes showed a high frequency of amplification (TERT, FCGR2B, CD79B and PRKAR1A) [63].