FGFR1 and gastrointestinal stromal tumor: In fact, in a comprehensive genomic study of a total of 14 qWT GIST patients performed by using whole-exome sequencing (WES) and gene expression analysis, a FGFR1 somatic missense mutation (c.1638C > A; p.N546K) was found in only one case, being the only oncogenic event identified [22].