INS and obesity due to melanocortin 4 receptor deficiency: Until now, however, the function and possible role of TSPOAP1-AS1 in diseases such as obesity remain unknown, but some studies suggested the possibility of relation between TSPOAP1-AS1 and obesity Blasi showed that the agonist of benzodiazepines receptor (translocator protein: TSPO) reduced body weight gain and lowered insulin level in obese rat [13].