INS and type 1 diabetes mellitus: Although participants recently started on insulin, or diagnosed when younger than age 35 years were excluded to remove those with type 1 diabetes, it is inevitable that this approach will have resulted in the unnecessary exclusion of some participants with T2DM and perhaps the inclusion of a small number of participants with type 1 diabetes who were diagnosed at older than age 35 and who were not treated with insulin within a year of that diagnosis.