CEBPA and nutritional deficiency disease: Transcriptional alterations of the hub genes were confirmed except for Atg9a. Additionally, through modeling miRNA–mRNA-transcription factor interactions for the hub genes, we confirmed a transcription factor, Cebpa, is essential to regulate the expression of Rhobtb2. We did not find singificent singals in the prefrontal cortex responding to maternal prenatal nutritional deficiency.