Examples include AK098656, which promotes hypertension through regulation of vascular smooth muscle cells (VSMCs) functions [24], GAS5, which promotes vascular remodeling and is downregulated in hypertension [25], and the TUG1/miR-145-5p/FGF10 axis, which regulates proliferation and migration in VSMCs [26]. The gene discussed is GAS5; the disease is hypertensive disorder.