We established ALL and BL cell lines infected with PRPS1 wild type (1‐wt), PRPS2 wild type (2‐wt), PRPS1 knocked out (1‐ko) and PRPS2 knocked out (2‐ko) retroviruses (Figure 3A,D, Figure S3A,C,E). This evidence concerns the gene PRPS2 and acute lymphoblastic leukemia.