We established ALL and BL cell lines infected with PRPS1 wild type (1‐wt), PRPS2 wild type (2‐wt), PRPS1 knocked out (1‐ko) and PRPS2 knocked out (2‐ko) retroviruses (Figure 3A,D, Figure S3A,C,E). The gene discussed is PRPS1; the disease is acute lymphoblastic leukemia.