Through the forest plot analysis (Figure 5), there are statistically significant linkages between gender (p = 0.019), distant metastasis (p = 0.022), neck lymph node metastasis (p = 0.002), the expression of IGF2BP2 (p = 0.025) and the outcome of HNSCC patients. The gene discussed is IGF2BP2; the disease is head and neck squamous cell carcinoma.