In neuronal glioblastoma (GBM) stem cells, an EGFR inhibitor [bevacizumab or temozolomide (TMZ)] combined with a late-stage autophagy blocker, chloroquine (CQ), improves drug toxicity, leading to the impairment of GBM CSC proliferation and survival (Golden et al., 2014; Huang et al., 2018). This evidence concerns the gene EGFR and glioblastoma.