In addition, in a xenograft mouse model of DLBCL induced by TMD8 cells with the MyD88 L265P mutation, we found that HJ901 treatment effectively inhibited tumor growth by inducing cell apoptosis and inhibiting Ki67 expression in tumor tissues, which is the hallmark of growth suppression measured by immune histochemical analysis (Jin et al., 2016). This evidence concerns the gene MYD88 and diffuse large B-cell lymphoma.