AKT1 and lung adenocarcinoma: miR-409-3p, maps to chromosome 14q32.31, and has been shown significantly downregulated in lung adenocarcinoma tissues when compared with corresponding noncancerous tissues, and can inhibit growth, migration, and invasion, as well as inducing apoptosis in lung adenocarcinoma cells via inactivation of Akt signaling by targeting c-Met (Wan et al., 2014).