On the other hand, transcriptomic analyses of peripheral blood mononuclear cells from TB patients revealed a dominant IFN gene signature, including those responding to type I and typed II (IFN-γ) signaling (Berry et al., 2010; Maertzdorf et al., 2012; Ottenhoff et al., 2012; Cliff et al., 2013). The gene discussed is IFNA1; the disease is tuberculosis.