PTGS2 and tuberculosis: Some of the 52 common genes in MoCT in response to infection with UT127 and UT205 included pro-inflammatory cytokines and chemokines such as IL1A, IL1B, IL6, IL23A, CCL20, TNF, TNFAIP6, CSF2, CCL1, CXCL1, and CXCL2 which are essential mediators of the inflammatory milieu in the lungs during TB; PTGS2 (COX-2, Cyclooxygenase-2), promotes the synthesis of prostaglandin E2 (PGE2) and is crucial for bacterial control.