Recently, a number of studies have demonstrated that serum lipid, such as total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein A-1 (ApoA-1) and apolipoprotein B (ApoB) were associated with several types of cancer risk (18–21). This evidence concerns the gene APOA1 and cancer.