TNFRSF1A and Autoimmunity: Impairing sTNFα-TNFR1 interaction by different strategies (sTNFα blockade, gene deletion or antibody blockade of TNFR1) can prevent autoimmunity, shedding light on the specific role of the sTNF-TNFR1 axis in inflammation (198) [reviewed in (199)].