INS and metabolic syndrome: Regarding metabolic parameters, BMI, fasting glucose, triglycerides, HDL-C, and MetS distributed equally between IGF-1 high and low groups as shown in Table 2 (all P > 0.05), while the distribution of blood pressure (P < 0.001), IGFBP-3 (P < 0.001), insulin (P < 0.001), C-peptide (P = 0.001), and the number of MetS components (P = 0.033) significantly differed by IGF-1expression.