For example, the Ras signaling pathway (required for the differentiation of slow muscle fibers by inducing slow motor neurons) (Murgia et al., 2000) contains specific eGenes associated with: GS - TGFA, RASGRF1; MS- RASGRP1, MAPK3, MAPK1, NFKB1, PLCG1, FLT1; and ALS- MRAS, TIAM1, FGF12. Here, MAPK1 is linked to amyotrophic lateral sclerosis.