Aldehyde dehydrogenase (ALDH) is a superfamily of 19 human isozymes and highly expressed in healthy as well as cancer cells with stem-like characteristics, however, ALDH expression is not limited to stem cells but also can be expressed by mature cells (Fillmore and Kuperwasser, 2008; Xu et al., 2015; Vassalli, 2019). This evidence concerns the gene LDHA and cancer.