LDHA and cancer: Moreover, healthy stem cells and CSCs can be differentiated by measuring the catalytic activity of ALDH that can also be used to monitor the prognosis of certain cancer patients (Ginestier et al., 2007; Deng et al., 2010; van den Hoogen et al., 2010; Marcato et al., 2011; Silva et al., 2011; Singh et al., 2015).