The study also found that ImmTAC-NYE-activated T cells release cytokines IFN-γ, IL-2, and TNF-α, which, in addition to attracting effector immune cells to the tumor site, may spur long-term anti-tumor activity by promoting components of the death receptor pathway in tumor cells, providing an additional mechanism of tumor cell killing even after the BsAb is metabolized (89, 216). Here, TNF is linked to neoplasm.