KIT and adrenal cortex carcinoma: Critical molecular alterations such as MYB-NFIB translocation, Sox 4, c-KIT, and Slug gene activation, overexpression of epidermal growth factors (EGFs), vascular endothelial growth factors (VEGFs), nerve growth factors (NGFs), and their corresponding receptors have been demonstrated to play essential roles in the pathogenesis of ACC by recent studies (13).