YAP1 and myocardial infarction: In the setting of MI, heterozygous inactivation of YAP1 in heart enhances CM apoptosis, fibrosis, enlarges infarct size, and impairs cardiac function; YAP1 activation using adeno-associated virus subtype 9: human YAP1 (AAV9: hYAP1) can alleviate MI injury and ameliorate cardiac function (Lin et al., 2014).