In particular, radiation-stimulated activation of Ca2+-dependent high conductance BK (KCa1.1, KCNMA1) (Steinle et al., 2011) and intermediate conductance IK (KCa3.1, SK4, KCNN4) K+ channels (Stegen et al., 2016) occurs in glioblastoma cells. The gene discussed is KCNMA1; the disease is glioblastoma.