To define the functional significance of radiation-stimulated hERG1-like channel activity, hERG1-dependent cell cycle progression of irradiated (0 or 5 Gy) primary CML cells was assessed by flow cytometry with propidium iodide Nicoletti staining of the DNA 24 h after irradiation (Figure 6D). Here, KCNH2 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.