SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Interestingly, Dravet syndrome—a genetic epilepsy associated, in most cases, with a loss-of-function de novo mutation in the SCN1A voltage-gated sodium channel subunit (Gataullina and Dulac, 2017)—is one particular form of childhood epilepsy where CBD has shown anticonvulsant activity.