RAB5A and infection: To further characterize the lysosome-like structure observed in TEM, we expressed early endosome, late endosome, and lysosome specific markers (Rab5, Rab7, and Lamp1, respectively) in neurons using a baculovirus-based transduction system (BacMam) and quantified the colocalization with P. gingivalis by HCS at 24 h and 48 h after infection.