DCA is proposed to induce cell apoptosis in ovarian cancer by inducing a shift from anaerobic to aerobic metabolism.18 To determine the effects of DCA on CSC subpopulations in SKOV3 cells, ALDH+CD44+ cells were treated with DCA (0, 5 and 10 mM) and subjected to the related functional assays. This evidence concerns the gene CD44 and ovarian carcinoma.