Histological examination of isolated tumours (Fig. 5e) revealed an average of ~41, ~30, ~40, and ~1 mitotic figures per high-power field (HPF) in tumour tissues isolated from mice treated with vehicle, Rom+Cis, Gem plus Cis, and Gem plus Rom+Cis, respectively (Fig. 5f, g). This evidence concerns the gene ROM1 and neoplasm.