Tumour-infiltrating microglia and macrophages display the pro-tumorigenic, immunosuppressive phenotype in gliomas.1 We studied the expression of genes recognised as markers of pro-tumorigenic (IL10, MYC) and inflammatory (IRF7, IL1B) phenotypes in primary human microglia cultures treated with LN18 and U87 glioma conditioned medium (GCM). This evidence concerns the gene IL1B and glioma.