In contrast, in adenocarcinoma and small cell carcinoma of the lung, SIRT1 seems to be associated with poor survival, which can also be observed in large B-cell lymphoma and in clear cell renal cell carcinomas (Chen et al. 2017; Jang et al. 2008; Noh Baek et al. 2013a, b; Noh Kang et al. 2013a, b; Wang and Wang 2016). This evidence concerns the gene SIRT1 and clear cell renal carcinoma.