For example, in our ceRNA network, we found MIR200HG-hsa-miR-146a-5p-SOX2 / HOXD10 axis in GBM, down-regulated lncRNA MIR200HG could competitively bound miRNAs (up-regulated), thereby indirectly encouraging targeted SOX2 / HOXD10 upregulation. This evidence concerns the gene HOXD10 and glioblastoma.