MGMT and neoplasm: As a result, telomerase reverse transcriptase (TERT) promoter mutation C250T (+ 52.4 ± 25.7 mm/year, p = 0.04) was significantly associated with increased tumor growth, while O-6-methylguanine-DNA methyltransferase (MGMT) promoter methylation (-37.4 ± 17.6 mm/year, p = 0.03) was significantly associated with decreased tumor growth.