These cells had a high expression of key inflammatory mediators previously implicated in myelofibrosis, including PDGFA, CCL5, and CXCL5 (Figures 5C and 5D) (Eliades et al., 2011, Malara et al., 2018, Mascarenhas et al., 2017). This evidence concerns the gene PDGFA and myelofibrosis.