For example, circNHSL1 served as an oncogenic circRNA in progression and metastasis of gastric cancer through the circNHSL1/miR-1306-3p/SIX1/Vimentin regulatory gene network [11]; circDONSON promoted progression and development of GC cells via the NURF complex-dependent activation of SOX4 signaling [12]. Here, SIX1 is linked to gastric cancer.