Considering that stress-induced dendritic changes were evident throughout the mPFC, we injected AAV-shNectin3 into the mPFC (infection rate: 62.14%) to knock down nectin3 levels in adolescent mice (29 days old) without focusing on specific subregions and examined its impact at the same time point as in the stress experiment (day 84, Figs. 5A, B, and S9A). This evidence concerns the gene NECTIN3 and infection.